Integrated Systems Engineering Srl, (ISE), was established in 1996, in Milan Italy.

With the development of the Galileo Tissue Microarrayer CK XXX Family one of the must appreciated TMA system in the field, has become one of the world leader in Tissue Microarrayer Instrumentation Design and Manufacturing.

The Galileo computer assisted TMA instrument with its open architecture allow an easy and simple TMA preparation (also with different paraffin block sizes) producing a digital excel format reporting and possibility of data transfer to several Digital TMA Slide Scanners(e.g Aperio.) for a complete tracking of the TMA process.

ISE has developed also the XBLOT instrument which is an Hybridization System which permits to save 90% of the antibody used during the western blot preparation.